From Medical Xpress
March 20, 2020
An underlying virus does not stop the body’s immune system from launching a strong defense against a second, newly introduced virus, according to a Yale-led study that appears in the March 9 online edition of the journal PLOS Neglected Tropical Diseases.
For the study, Yale researchers obtained blood samples from patients from India with dengue infection, working in partnership with investigators from The National Institute of Mental Health and NeuroSciences in India and their colleagues at Apollo Hospital in Bangalore. They then infected these samples with the Zika virus and measured the cells’ immune response using advanced cell-profiling technology. The researchers found that the underlying dengue infection did not stop the cells from launching a robust immune response against the newly introduced Zika virus.